منابع مشابه
Soft Tissue and Uterine Leiomyosarcoma.
Leiomyosarcoma (LMS) is one of the most common subtypes of soft tissue sarcoma in adults and can occur in almost any part of the body. Uterine leiomyosarcoma is the most common subtype of uterine sarcoma. Increased awareness of this unique histology has allowed for the development of drugs that are specific to LMS and has begun to shed light on the similarities and possible unique aspects of so...
متن کاملLeiomyosarcoma of the soft palate.
Tumors of the smooth muscles are rarely seen, as the number of smooth muscles is low within the intraoral region. Leiomyosarcoma is a type of malign tumor originating from smooth muscles. The most common regions of leiomyosarcoma of the oral cavity are the maxilla and mandible. In this article, we present a leiomyosarcoma detected in a 20-year-old male patient who was admitted to the clinic wit...
متن کاملExpression profiling in soft tissue sarcomas with emphasis on synovial sarcoma, gastrointestinal stromal tumor, and leiomyosarcoma.
Sarcomas are defined as malignant neoplasms derived from mesenchymal tissues. A variety of different molecular approaches, including gene expression profiling, have identified candidate biomarkers and insights into sarcoma biology that will aid in the diagnosis and treatment of these tumors. Many gene expression profiling findings have been translated into immunohistochemical tests for diagnost...
متن کاملCASE REPORT Soft tissue, pelvic, and urinary bladder leiomyosarcoma as second neoplasm following hereditary retinoblastoma
This report describes two patients who developed leiomyosarcomas, one involving the subcutaneous tissue of the thigh and the pelvic soft tissues and the other the urinary bladder, following hereditary retinoblastoma 36 and 38 years earlier, respectively. There is an increased risk of the development of sarcoma, most commonly osteosarcoma, as a second malignancy following hereditary retinoblasto...
متن کاملEfficacy of trabectedin in advanced soft tissue sarcoma: beyond lipo- and leiomyosarcoma
OBJECTIVE Trabectedin is effective in leiomyosarcoma and liposarcoma, especially the myxoid variant, related to the presence of the FUS-CHOP transcript. We evaluated the efficacy of trabectedin in specific subgroups of patients with soft tissue sarcomas (STS). METHODS Seventy-two patients with advanced anthracycline-pretreated STS, who received trabectedin at a dose of 1.5 mg/m(2) every 3 wee...
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ژورنال
عنوان ژورنال: Mayo Clinic Proceedings
سال: 2019
ISSN: 0025-6196
DOI: 10.1016/j.mayocp.2019.09.011